Efficient catalytic cyclizations of three and two imine assemblies: direct access to tetrahydroimidazo[1,5-c]imidazol-7-ones and imidazoles.
نویسندگان
چکیده
A cascade cyclization involving union of three imines by an organocatalyst proline is established to afford new fused-tetrahydroimidazo[1,5-c]imidazol-7-ones with excellent regio- and stereoselectivity. Another dehydrogenative cyclization by union of two imines is developed using the Cu(OTf)(2)-Ag(2)O combo catalyst to furnish functionalized imidazoles.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 52 شماره
صفحات -
تاریخ انتشار 2012